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Background and importance. Ulcerative proctitis is associated with faecal incontinence, pain, itching, bleeding and purulent discharge, and is often managed with topical salicylates or steroids. However, treatment can be refractory in some patients. Rectal administration of tacrolimus may be effective in difficult to treat ulcerative proctitis 1 . Some patients find it difficult to retain rectal pharmaceutical forms, suppositories or enemas, which lead to painful administration and infradosification. Aim and objectives. To develop a tacrolimus adhesive gel and its galenic validation, to improve and extend contact time of tacrolimus with rectal mucosal surfaces. Material and methods. Tacrolimus 0.06% adhesive gel was compounded, in a biological.
PlasticsToday 06/02/2020 10:49
Nordson Corp. announced yesterday the acquisition of Fluortek Inc., a precision plastic extrusion manufacturer based in Easton, PA, that provides custom tubing to the medical device industry. "As Nordson Medical continues to expand its differentiated product offerings, the acquisition of Fluortek enhances our ability to deliver critical components that enable our customers’ most complex medical device innovations," said Jeffrey Pembroke, Executive Vice President, Nordson Advanced Technology Solutions.
Inderscience (EU) 06/01/2020 16:54
Purified terephthalic acid (PTA) is the raw material for polyester fibres, plastics, coating and adhesives. Its manufacture generates large volumes of effluent with high concentration of terephthalic acid (500-600 ppm), a critical pollutant. In this study a mixed culture made up of five types of bacteria, derived from the effluent treatment plant (ETP) sludge was used to aerobically treat the PTA effluent, removing all the benzoates [4-carboxybenzyl alcohol, isophthalic acid, terephthalic acid, 4-carboxy benzaldehyde (4-CBA), benzoic acid, p-toluic acid and trimellitic acid] which contribute to its chemical oxygen demand (COD). The study included optimisation of pH (6-9), pH neutralisers and biomass concentration (≥2,000 ppm Mixed liquor su.
GlobeNewswire 06/01/2020 11:06
TORONTO, June 01, 2020 (GLOBE NEWSWIRE) -- CCL Industries Inc. ("CCL") (TSX:CCL.A) (TSX:CCL.B), a world leader in specialty label and packaging solutions for global corporations, small businesses and consumers, announced today the closing of its offering of US$600 million aggregate principal amount of 3.050% notes due 2030.

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