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FeedNavigator (EU) 10/22/2019 06:22
At 16 weeks, there was diffuse SGLT1 expression in the hepatic lobules and strong expression by hepatocytes in the vehicle group, while SGLT2 expression was stronger in liver tumors than in the lobules.
Pharmafile 10/21/2019 04:52
New Phase 3 data has emerged demonstrating the efficacy of Roche’s Tecentriq (atezolizumab) in combination with Avastin (bevacizumab) in the treatment of unresectable hepatocellular carcinoma (HCC) in patients who have not received prior systemic therapy. The results, drawn from a trial of 501 unresectable HCC patients, showed that the pair of drugs met the trial’s co-primary endpoints, generating "statistically significant and clinically meaningful improvements" in both overall survival and progression-free survival compared to Nexavar (sorafenib), the current standard of care.

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